The program works in the background, tracing all devices connected to your computer. When it recognizes a new connection, it starts working.
This application also helps keep your system safe, since it stops a USB memory from automatically running if it finds that it has been infected by any type of virus or malware. You can modify this at any time, and create a list of approved programs to be opened, so you can access them even if the tool has detected a different problem with the drive.
Autorun USB Helper is a complete tool that will help you keep USB memories from damaging your computer, since they often become virus carriers.